Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 2/20 | 0.69 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.69 |
| ▸ | MEN1 | O00255 | 1/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 1/20 | 0.64 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.64 |
| ▸ | TSHR | P16473 | 1/20 | 0.64 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.64 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
| ▸ | DRD3 | P35462 | 6/20 | 0.57 |
| ▸ | DRD2 | P14416 | 5/20 | 0.57 |
| ▸ | HTR1A | P08908 | 3/20 | 0.57 |
| ▸ | HTR2A | P28223 | 3/20 | 0.57 |
| ▸ | HTR7 | P34969 | 3/20 | 0.57 |
| ▸ | DRD1 | P21728 | 2/20 | 0.57 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5425425 | 0.87 | MEN1 (0.64) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5431884 | 0.83 | MAPT (0.88) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5438985 | 0.81 | MEN1 (0.73) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL8879725 | 0.79 | MEN1 (0.75) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL10726259 | 0.79 | KDM4E (0.53) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5435317 | 0.78 | MAPT (0.78) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL2216839 | 0.78 | MAPT (1.00) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5439549 | 0.77 | MAPT (0.69) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5424036 | 0.77 | MAPT (0.69) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 | |
| SCHEMBL5430624 | 0.77 | MAPT (0.69) | SLC6A4SLC6A2MEN1CYP1A2CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57114588-A | — | — | None | — | — | JP | disclosed |
| JP-59007120-A | — | — | None | — | — | JP | disclosed |
| JP-S597120-A | HYPOTENSIVE AGENT | MITSUBISHI CHEM IND LTD | 1984-01-14 | — | — | JP | disclosed |
| JP-S57114588-A | (OMEGA-PIPERAZINYLALKOXY)ALKYLENEDIOXYBENZENE AND ITS ACID ADDITION SALT | MITSUBISHI CHEM IND LTD | 1982-07-16 | — | — | JP | disclosed |