Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.78 |
| ▸ | MEN1 | O00255 | 1/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.78 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.78 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.78 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.78 |
| ▸ | TSHR | P16473 | 1/20 | 0.78 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.78 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.78 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.78 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.78 |
| ▸ | SLC6A2 | P23975 | 3/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.62 |
| ▸ | DRD2 | P14416 | 7/20 | 0.62 |
| ▸ | DRD3 | P35462 | 5/20 | 0.62 |
| ▸ | HTR1A | P08908 | 3/20 | 0.62 |
| ▸ | HTR2A | P28223 | 2/20 | 0.62 |
| ▸ | HRH1 | P35367 | 1/20 | 0.62 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5430624 | 0.96 | MAPT (0.69) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5431884 | 0.93 | MAPT (0.88) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5432917 | 0.90 | MAPT (0.79) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL2216839 | 0.88 | MAPT (1.00) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5424036 | 0.84 | MAPT (0.69) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5439549 | 0.84 | MAPT (0.69) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5425415 | 0.81 | KDM4E (0.70) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| Maleic Acid SCHEMBL1935564 | 0.80 | MAPT (0.84) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| Fumaric Acid SCHEMBL1935565 | 0.80 | MAPT (0.84) | MAPTMEN1CYP1A2CYP3A4CYP2D6 | |
| SCHEMBL5438999 | 0.79 | KDM4E (0.67) | MAPTMEN1CYP1A2CYP3A4CYP2D6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070219213-A1 | Use of Adrenergic N-Phenylpiperazine Antagonists, Pahrmaceutical Compositions Containning Them, and Methods of Preparing Them | UNIAO BRASILIENSE DE EDUCACAO E CULTURA-UBEC (BR) | 2007-09-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070219213-A1 | Use of Adrenergic N-Phenylpiperazine Antagonists, Pahrmaceutical Compositions Containning Them, and Methods of Preparing Them | ADRA1D, ADRB1, ADRA1A | MAPT 1078/4885MEN1 1791/4885CYP1A2 87/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.