Chromocarb

Chromocarb

SCHEMBL11033175

NC(=O)CNc1ccccc1.O=C(O)c1cc(=O)c2ccccc2o1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 1/20 0.69
USP2 O75604 1/20 0.69
CSNK2A2 P19784 1/20 0.69
PTGS1 P23219 1/20 0.69
CSNK2B P67870 1/20 0.69
CSNK2A1 P68400 1/20 0.69
CSNK2A3 Q8NEV1 1/20 0.69
LMNA P02545 1/20 0.59
KMT2A Q03164 5/20 0.50
MEN1 O00255 4/20 0.50
MAOB P27338 3/20 0.50
MAOA P21397 2/20 0.50
CAPN1 P07384 1/20 0.49
RXFP1 Q9HBX9 1/20 0.49
POLB P06746 2/20 0.49
MAPT P10636 2/20 0.49
ALDH1A1 P00352 2/20 0.49
NPC1 O15118 1/20 0.49
HTT P42858 1/20 0.49
RAB9A P51151 1/20 0.49

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chromocarb SCHEMBL432304 0.83 KDM4E (1.00) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL29355904 0.83 KDM4E (1.00) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL29695542 0.82 KDM4E (0.96) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL28113935 0.82 KDM4E (0.96) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL27958709 0.82 KDM4E (0.96) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL6633182 0.82 KDM4E (0.96) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL11033173 0.80 CSNK2A2 (0.69) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL29537823 0.79 KDM4E (0.77) KDM4EUSP2CSNK2A2PTGS1CSNK2B
Chromocarb SCHEMBL3909750 0.79 KDM4E (0.77) KDM4EUSP2CSNK2A2PTGS1CSNK2B
SCHEMBL5206502 0.79 LMNA (0.72) KDM4EUSP2CSNK2A2PTGS1CSNK2B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-59108778-A None JP disclosed
JP-S59108778-A NOVEL BETA-LACTAM AND ANTIBACTERIAL AGENT TEIJIN LTD 1984-06-23 JP disclosed