Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 3/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 3/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | IDO1 | P14902 | 3/20 | 0.43 |
| ▸ | HRH1 | P35367 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.40 |
| ▸ | HTR3A | P46098 | 1/20 | 0.40 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.39 |
| ▸ | HTR2C | P28335 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.36 |
| ▸ | BRD4 | O60885 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19839314 | 0.81 | IDO1 (0.53) | HTR1AIDO1GPR84BRD4CYP3A4 | |
| SCHEMBL11554549 | 0.74 | SLC6A2 (0.44) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL19839262 | 0.72 | IDO1 (0.55) | SLC6A4ADRA1AIDO1GPR84 | |
| SCHEMBL8366383 | 0.72 | SLC6A4 (0.48) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL7258599 | 0.70 | IDO1 (0.63) | HTR2AADRA1AADRA2CIDO1GPR84 | |
| SCHEMBL2924439 | 0.69 | HTR2A (0.65) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL2925939 | 0.69 | HTR2A (0.65) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL1002267 | 0.69 | HTR2A (0.65) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL11634137 | 0.68 | HTR2A (0.59) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 | |
| SCHEMBL31381398 | 0.68 | SLC6A2 (0.56) | SLC6A4HTR2ASLC6A2HTR2BSLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59059676-A | — | — | None | — | — | JP | disclosed |
| JP-S5959676-A | NOVEL MORPHOLINE DERIVATIVE AND ITS PREPARATION | YAMANOUCHI PHARMACEUT CO LTD | 1984-04-05 | — | — | JP | disclosed |