Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A4 | P31645 | 9/20 | 0.48 |
| ▸ | SLC6A2 | P23975 | 8/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.48 |
| ▸ | HTR2A | P28223 | 4/20 | 0.48 |
| ▸ | HTR2B | P41595 | 2/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.48 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.48 |
| ▸ | HTR3A | P46098 | 1/20 | 0.48 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.48 |
| ▸ | HTR1D | P28221 | 2/20 | 0.41 |
| ▸ | HTR1B | P28222 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11079827 | 0.81 | TDP1 (0.42) | HTR2ACYP1A2CYP3A4 | |
| SCHEMBL11553490 | 0.74 | SLC6A2 (0.44) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL11033495 | 0.72 | SLC6A4 (0.48) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL2925939 | 0.69 | HTR2A (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL2924439 | 0.69 | HTR2A (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL1002267 | 0.69 | HTR2A (0.65) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL26668485 | 0.68 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL26668478 | 0.68 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL31381398 | 0.68 | SLC6A2 (0.56) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B | |
| SCHEMBL971425 | 0.67 | SLC6A2 (0.55) | SLC6A4SLC6A2SLC6A3HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999043302-A1 | STABILIZING COMPOSITION FOR PHARMACEUTICAL DOSAGE FORMS | WATSON PHARMACEUTICALS, INC. (US) | 1999-09-02 | — | — | WO | claimed |
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | claimed |
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |
| US-4109088-A | ANTIDEPRESSANTS | YAMANOUCHI PHARMACEUTICAL CO., LTD. (JP) | 1978-08-22 | — | — | US | disclosed |