SCHEMBL11033574

SCHEMBL11033574

[CH]C1C2CC3CC(C2)CC1C3

nearest known ligand 0.44

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
CYP2C9 P11712 1/20 0.44
EPHX2 P34913 1/20 0.33
HSD11B1 P28845 1/20 0.32
CYP2A13 Q16696 1/20 0.31
CA1 P00915 1/20 0.31
CA2 P00918 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Adamantane SCHEMBL28785912 0.69 CYP2C9 (0.40) CYP2C9
Adamantane SCHEMBL12761 0.68 CYP2C9 (0.46) CYP2C9EPHX2HSD11B1
Adamantane SCHEMBL1527414 0.68 CYP2C9 (0.46) CYP2C9EPHX2HSD11B1
Adamantane SCHEMBL29707714 0.68 CYP2C9 (0.46) CYP2C9EPHX2HSD11B1
Adamantane SCHEMBL9016497 0.68 CYP2C9 (0.46) CYP2C9EPHX2HSD11B1
SCHEMBL2189873 0.67 CYP2C9 (0.50) CYP2C9EPHX2HSD11B1CYP2A13CA1
SCHEMBL10459155 0.64 CYP2C9 (0.47) CYP2C9EPHX2HSD11B1CYP2A13CA1
Adamantane SCHEMBL25252048 0.63 CYP2C9 (0.43) CYP2C9EPHX2
Adamantane SCHEMBL21820021 0.63 CYP2C9 (0.43) CYP2C9EPHX2
Adamantane SCHEMBL21192802 0.63 CYP2C9 (0.43) CYP2C9EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4424387-A STRONG ACID, BRANCHING EXXON RESEARCH AND ENGINEERING CO. (US) 1984-01-03 US disclosed