Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PREP | P48147 | 5/20 | 0.36 |
| ▸ | DPP4 | P27487 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | ACE | P12821 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
| ▸ | CASP1 | P29466 | 2/20 | 0.32 |
| ▸ | STS | P08842 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11034295 | 0.98 | PREP (0.38) | PREPDPP4ACEMEN1KMT2A | |
| SCHEMBL11045501 | 0.98 | PREP (0.38) | PREPDPP4ACEMEN1KMT2A | |
| SCHEMBL11035261 | 0.98 | PREP (0.38) | PREPDPP4ACEMEN1KMT2A | |
| SCHEMBL10788524 | 0.85 | DPP4 (0.39) | PREPDPP4CYP3A4ACEALOX15 | |
| SCHEMBL10957344 | 0.85 | PREP (0.42) | PREPCYP3A4ACEALOX15MEN1 | |
| SCHEMBL10437288 | 0.83 | ACE (0.41) | PREPDPP4CYP3A4ACEALOX15 | |
| SCHEMBL10958744 | 0.83 | PREP (0.44) | PREPACEMEN1KMT2ALMNA | |
| SCHEMBL10960000 | 0.83 | PREP (0.44) | PREPACEMEN1KMT2ALMNA | |
| SCHEMBL10960908 | 0.83 | PREP (0.44) | PREPACEMEN1KMT2ALMNA | |
| SCHEMBL10960970 | 0.83 | PREP (0.44) | PREPACEMEN1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0126986-A1 | Process for producing N-alkylated dipeptides and their esters | HOECHST AKTIENGESELLSCHAFT (DE) | 1984-12-05 | — | — | EP | disclosed |