Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 5/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | DPP4 | P27487 | 1/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10437321 | 0.94 | PREP (0.45) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10437333 | 0.93 | PREP (0.42) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10788524 | 0.91 | DPP4 (0.39) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9356920 | 0.86 | HTR2C (0.46) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10437302 | 0.85 | CYP1A2 (0.42) | PREP | |
| SCHEMBL10437314 | 0.83 | PREP (0.42) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL11033625 | 0.83 | PREP (0.36) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL10437301 | 0.83 | ACHE (0.39) | KMT2ANPC1ALDH1A1HPGDSMN1; SMN2 | |
| SCHEMBL10511673 | 0.83 | HRH1 (0.42) | ACEMEN1KMT2ACYP3A4ALOX15 | |
| SCHEMBL9775269 | 0.82 | ACE (0.46) | ACEMEN1KMT2ACYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0370378-A2 | Pyrrolidine-2-carboxylic-acid derivatives with a psychotropic activity | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-05-30 | — | — | EP | disclosed |