Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.41 |
| ▸ | THRB | P10828 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Ethyl Ester SCHEMBL1532604 | 0.96 | TSHR (0.61) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL29285339 | 0.94 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9768543 | 0.93 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9776651 | 0.91 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL719063 | 0.91 | TSHR (0.71) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL29919002 | 0.90 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Styrene SCHEMBL4817683 | 0.89 | TSHR (0.52) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8899313 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8547396 | 0.88 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL8382799 | 0.87 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4429066-A | AUTOMOBILES AND TRUCKS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1984-01-31 | — | — | US | disclosed |