Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 9/20 | 0.54 |
| ▸ | HPGD | P15428 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | HCAR2 | Q8TDS4 | 3/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | APEX1 | P27695 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4790718 | 0.90 | TSHR (0.54) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL27679854 | 0.90 | TSHR (0.59) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL11033656 | 0.90 | TSHR (0.67) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL1133908 | 0.89 | TSHR (0.58) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Ethylene Glycol SCHEMBL16819031 | 0.88 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL2018446 | 0.88 | TSHR (0.65) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Itaconate SCHEMBL6247056 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL28182706 | 0.88 | TSHR (0.56) | TSHRHPGDALDH1A1CYP3A4ATM | |
| SCHEMBL9443412 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM | |
| Methacrylic Acid SCHEMBL10809413 | 0.87 | TSHR (0.63) | TSHRHPGDALDH1A1CYP3A4ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114958277-A | Single-component moisture-curing reaction type polyurethane hot melt adhesive and preparation method thereof | 北京高盟新材料股份有限公司 | 2022-08-30 | — | — | CN | disclosed |