Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL11531418 | 0.78 | ALDH1A1 (0.32) | ALDH1A1HSD17B10CYP3A4TSHR | |
| SCHEMBL10109491 | 0.75 | ALDH1A1 (0.53) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL9343797 | 0.74 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL11123962 | 0.74 | ALDH1A1 (0.64) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| Ethion SCHEMBL26750 | 0.74 | ALDH1A1 (0.68) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL8535140 | 0.74 | ALDH1A1 (0.78) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL10109441 | 0.74 | ALDH1A1 (0.52) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL10902629 | 0.72 | — | — | |
| Ethion SCHEMBL8388102 | 0.72 | ALDH1A1 (0.65) | ALDH1A1HSD17B10CYP3A4TSHRMEN1 | |
| SCHEMBL10906763 | 0.71 | ALDH1A1 (0.30) | ALDH1A1HSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4450157-A | INSECTICIDES | HOFFMANN-LA ROCHE INC. (US) | 1984-05-22 | — | — | US | disclosed |