SCHEMBL11033679

SCHEMBL11033679

CCCCCCCNNC(N)=S

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC1 Q13547 4/20 0.41
HDAC3 O15379 3/20 0.41
HDAC2 Q92769 3/20 0.41
EPHX1 P07099 7/20 0.41
HDAC11 Q96DB2 2/20 0.39
HDAC8 Q9BY41 1/20 0.39
HDAC6 Q9UBN7 1/20 0.39
ALDH1A1 P00352 2/20 0.39
TSHR P16473 1/20 0.39
HPGD P15428 1/20 0.38
HSD17B10 Q99714 1/20 0.38
SPHK2 Q9NRA0 1/20 0.37
SPHK1 Q9NYA1 1/20 0.37
ADH1B P00325 1/20 0.37
ADH1C P00326 1/20 0.37
ADH1A P07327 1/20 0.37
ADH4 P08319 1/20 0.37
ADH7 P40394 1/20 0.37
GBA1 P04062 1/20 0.36
CASP2 P42575 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6111687 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL28415125 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL28059471 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL28059479 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL11226737 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL28968579 1.00 HDAC1 (0.41) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL41078 0.98 ALDH1A1 (0.40) HDAC1HDAC3HDAC2EPHX1HDAC11
SCHEMBL721193 0.91
SCHEMBL1489137 0.81
SCHEMBL11032495 0.78 EPHX1 (0.50) HDAC1HDAC3HDAC2EPHX1HDAC11

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4447571-A WITH ALKYL AMINES AND HYDRAZIDES; DISCOLORATION INHIBITION WITCO CHEMICAL CORPORATION (US) 1984-05-08 US disclosed