Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 1/20 | 0.55 |
| ▸ | TSHR | P16473 | 1/20 | 0.55 |
| ▸ | PLA2G4B | P0C869 | 8/20 | 0.53 |
| ▸ | RARB | P10826 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 2/20 | 0.51 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | APEX1 | P27695 | 1/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.48 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11033028 | 1.00 | TP53 (0.55) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11031528 | 1.00 | TP53 (0.55) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11034638 | 1.00 | TP53 (0.55) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11032310 | 0.99 | TP53 (0.52) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11033909 | 0.90 | GAA (0.60) | POLBTDP1GAA | |
| SCHEMBL11034052 | 0.89 | GAA (0.44) | TP53TSHRPLA2G4BRARBHTT | |
| SCHEMBL11033885 | 0.89 | PARP10 (0.46) | TP53TSHRTDP1GAA | |
| SCHEMBL11034168 | 0.88 | CYP1A2 (0.45) | TP53TSHRHTTTDP1GAA | |
| SCHEMBL11031023 | 0.88 | MAPT (0.54) | TP53HTTTDP1GAA | |
| SCHEMBL11031794 | 0.88 | KMT2A (0.54) | PLA2G4B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111345-A2 | Isoxazoles, useful as antiviral agents, and preparation thereof | STERLING DRUG INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | disclosed |