Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.40 |
| ▸ | NPC1 | O15118 | 3/20 | 0.39 |
| ▸ | RAB9A | P51151 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.39 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.39 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11031528 | 0.89 | TP53 (0.55) | GAATDP1TP53TSHRPLA2G4B | |
| SCHEMBL11033892 | 0.89 | TP53 (0.55) | GAATDP1TP53TSHRPLA2G4B | |
| SCHEMBL11033028 | 0.89 | TP53 (0.55) | GAATDP1TP53TSHRPLA2G4B | |
| SCHEMBL11033909 | 0.89 | GAA (0.60) | GAACYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL11034638 | 0.89 | TP53 (0.55) | GAATDP1TP53TSHRPLA2G4B | |
| SCHEMBL11033885 | 0.88 | PARP10 (0.46) | GAACYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL11032310 | 0.88 | TP53 (0.52) | GAATDP1TP53TSHRPLA2G4B | |
| SCHEMBL11034168 | 0.87 | CYP1A2 (0.45) | GAACYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL11031023 | 0.87 | MAPT (0.54) | GAACYP1A2CYP19A1CYP2C9CYP2C19 | |
| SCHEMBL11030990 | 0.86 | GPR119 (0.46) | GAACYP1A2CYP19A1CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0111345-A2 | Isoxazoles, useful as antiviral agents, and preparation thereof | STERLING DRUG INC. (US) | 1984-06-20 | — | — | EP | disclosed |
| US-4451476-A | Isoxazoles as antiviral agents | STERLING DRUG INC. (US) | 1984-05-29 | — | — | US | disclosed |