Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXAS1 | P24557 | 17/20 | 0.75 |
| ▸ | PTGIR | P43119 | 2/20 | 0.42 |
| ▸ | ESR1 | P03372 | 1/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11006110 | 0.88 | TBXAS1 (0.78) | TBXAS1PTGIRESR1ESR2 | |
| SCHEMBL11037062 | 0.88 | TBXAS1 (0.57) | TBXAS1PTGIRESR1ESR2 | |
| SCHEMBL10451457 | 0.87 | TBXAS1 (0.76) | TBXAS1PTGIRESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11004741 | 0.86 | TBXAS1 (0.75) | TBXAS1PTGIRESR1ESR2 | |
| SCHEMBL11009473 | 0.86 | TBXAS1 (1.00) | TBXAS1PTGIR | |
| SCHEMBL3513494 | 0.86 | TBXAS1 (1.00) | TBXAS1PTGIR | |
| SCHEMBL11006075 | 0.86 | TBXAS1 (1.00) | TBXAS1PTGIR | |
| SCHEMBL11013586 | 0.86 | TBXAS1 (0.74) | TBXAS1 | |
| SCHEMBL7811725 | 0.86 | TBXAS1 (0.69) | TBXAS1PTGIRESR1ESR2 | |
| Hydrochloric Acid SCHEMBL11008442 | 0.85 | TBXAS1 (0.72) | TBXAS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4478842-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-10-23 | — | — | US | claimed |
| EP-0080154-B1 | N-SUBSTITUTED 2-PYRIDYL INDOLES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM, AND THEIR THERAPEUTICAL USE | CIBA-GEIGY AG (CH) | 1985-08-28 | — | — | EP | disclosed |
| US-4478842-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-10-23 | — | — | US | disclosed |
| US-4460777-A | THROMBOXANE SYNTHETASE INHIBITORS | CIBA-GEIGY CORPORATION (US) | 1984-07-17 | — | — | US | disclosed |
| EP-0080154-A2 | N-substituted 2-pyridyl indoles, process for their preparation, pharmaceutical compositions containing them, and their therapeutical use | CIBA-GEIGY AG (CH) | 1983-06-01 | — | — | EP | disclosed |