SCHEMBL11033922

SCHEMBL11033922

CCOC=C(C(=O)O)C(=O)CCl

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
EP300 Q09472 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5697356 0.83 EP300 (0.32) EP300
SCHEMBL30444526 0.83 EP300 (0.32) EP300
SCHEMBL1421463 0.83 EP300 (0.37) EP300
SCHEMBL9298250 0.81 NPSR1 (0.46)
SCHEMBL9298246 0.81 NPSR1 (0.46)
SCHEMBL10532369 0.80 CES2 (0.42) EP300
SCHEMBL4000343 0.80 CES2 (0.42) EP300
SCHEMBL19463261 0.78
SCHEMBL19463260 0.78
SCHEMBL20768133 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116120287-A Heteroaromatic carboxamide derivatives as inhibitors of plasma kallikrein 勃林格殷格翰国际有限公司 2023-05-16 CN disclosed
EP-0112321-A1 Enamine derivatives of phosphonic acid esters MONSANTO COMPANY (US) 1984-06-27 EP disclosed
US-4444582-A Enamine derivatives of phosphonic acid esters as herbicides MONSANTO COMPANY (US) 1984-04-24 US disclosed