Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | TLR4 | O00206 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | CCR2 | P41597 | 1/20 | 0.35 |
| ▸ | NAAA | Q02083 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11028782 | 0.95 | PKM (0.43) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11030484 | 0.94 | HTT (0.45) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11026807 | 0.90 | TLR4 (0.46) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11029534 | 0.86 | CYP1A2 (0.43) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11029323 | 0.86 | PKM (0.42) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11033011 | 0.85 | MEN1 (0.43) | POLBHPGDHTTMAPTPKM | |
| SCHEMBL13267652 | 0.85 | PKM (0.51) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11029152 | 0.84 | TLR4 (0.42) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL13267644 | 0.84 | HTT (0.55) | POLBHPGDHTTLMNAMAPK1 | |
| SCHEMBL11030666 | 0.83 | PKM (0.43) | POLBHPGDHTTLMNAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4432885-A | Decalins | HOFFMANN-LA ROCHE INC. (US) | 1984-02-21 | — | — | US | disclosed |