Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.38 |
| ▸ | GAA | P10253 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | MGAM | O43451 | 1/20 | 0.35 |
| ▸ | SI | P14410 | 1/20 | 0.35 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.35 |
| ▸ | SOAT1 | P35610 | 1/20 | 0.35 |
| ▸ | CAD | P27708 | 1/20 | 0.34 |
| ▸ | MMP8 | P22894 | 1/20 | 0.34 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1060218 | 0.98 | ALDH1A1 (0.39) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL27491666 | 0.95 | ALDH1A1 (0.37) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL28077349 | 0.82 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL230068 | 0.79 | ALDH1A1 (0.50) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL27914453 | 0.79 | GAA (0.39) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| Dimethylamine SCHEMBL15710606 | 0.78 | GAA (0.46) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL28125171 | 0.77 | TSHR (0.33) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL28135604 | 0.77 | HDAC4 (0.33) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| SCHEMBL28054134 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 | |
| Ammonia Solution, Strong SCHEMBL27830684 | 0.77 | ALDH1A1 (0.48) | ALDH1A1GAAHPGDRECQLSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4483853-A | ANTICONVULSANTS | COLLINS JAMES F | 1984-11-20 | — | — | US | disclosed |
| US-4477391-A | Amino acid isomers, their production and their medicinal use | COLLINS JAMES F (GB) | 1984-10-16 | — | — | US | disclosed |