Known targets — ChEMBL curated mechanism
ACHEADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3APH1AAPH1BCHRM2CHRM3EZH2GRIN2AHTR1AHTR1BHTR1DHTR1FHTR3ANCSTNP2RY12PSEN1PSEN2PSENENSIGMAR1SLC6A2SLC6A3SLC6A4
The experimentally established mechanism targets of Bromide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL919086 | 0.81 | — | — | |
| SCHEMBL270443 | 0.75 | LMNA (0.34) | — | |
| SCHEMBL8415249 | 0.75 | LMNA (0.30) | — | |
| SCHEMBL12190430 | 0.73 | LMNA (0.31) | — | |
| SCHEMBL25311427 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL230510 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL20011690 | 0.72 | LMNA (0.32) | — | |
| SCHEMBL25200834 | 0.71 | HTT (0.35) | — | |
| Hydrochloric Acid SCHEMBL28860979 | 0.71 | LMNA (0.32) | — | |
| Hydrochloric Acid SCHEMBL27888944 | 0.71 | LMNA (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59005195-A | — | — | None | — | — | JP | disclosed |
| JP-S595195-A | TRIALKOXYSILANE SUBSTITUTED WITH HALOALKYLAMINO GROUP AND ITS PREPARATION | TOKUYAMA SODA CO LTD | 1984-01-12 | — | — | JP | disclosed |