Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.48 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.48 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.48 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.48 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.48 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.48 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.46 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL723060 | 0.85 | ALDH1A1 (0.50) | LMNAMAPTGAAF2PRSS1 | |
| SCHEMBL3254319 | 0.85 | ALDH1A1 (0.50) | LMNAMAPTGAAF2PRSS1 | |
| SCHEMBL3725641 | 0.85 | ALDH1A1 (0.50) | LMNAMAPTGAAF2PRSS1 | |
| SCHEMBL10627962 | 0.83 | KMT2A (0.42) | LMNAMAPTALDH1A1MEN1KMT2A | |
| SCHEMBL29179755 | 0.78 | NPC1 (0.58) | NPC1CYP3A4MAPTGAAF2 | |
| SCHEMBL27880968 | 0.77 | KMT2A (0.53) | NPC1CYP3A4LMNAMAPTGAA | |
| SCHEMBL5402167 | 0.75 | POLB (0.52) | NPC1GRIN2DGRIN3BGRIN1GRIN2A | |
| SCHEMBL5399851 | 0.75 | POLB (0.52) | NPC1GRIN2DGRIN3BGRIN1GRIN2A | |
| Guanidine SCHEMBL5918487 | 0.75 | NPC1 (0.50) | NPC1CYP3A4MAPTGAAF2 | |
| SCHEMBL8430250 | 0.74 | CA12 (0.43) | LMNAMAPTGAAPRSS1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59128364-A | — | — | None | — | — | JP | disclosed |
| JP-S59128364-A | PREPARATION OF OPTICALLY ACTIVE ALANINE | TANABE SEIYAKU CO LTD | 1984-07-24 | — | — | JP | disclosed |