Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.53 |
| ▸ | CA2 | P00918 | 2/20 | 0.53 |
| ▸ | KRAS | P01116 | 1/20 | 0.53 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.51 |
| ▸ | CTSL | P07711 | 1/20 | 0.50 |
| ▸ | CTSB | P07858 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | NPC1 | O15118 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 1/20 | 0.49 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.49 |
| ▸ | RELA | Q04206 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27466400 | 0.81 | F3 (0.66) | CYP1B1ALDH1A1LMNAMEN1KMT2A | |
| SCHEMBL8312374 | 0.81 | CYP1A2 (0.58) | KRASCYP1B1CTSLCTSBALDH1A1 | |
| SCHEMBL6443181 | 0.81 | CYP1A2 (0.58) | KRASCYP1B1CTSLCTSBALDH1A1 | |
| SCHEMBL11882381 | 0.80 | AKT1 (0.59) | CYP1B1ALDH1A1HTTLMNAMEN1 | |
| SCHEMBL7529869 | 0.80 | AKT1 (0.59) | CYP1B1ALDH1A1HTTLMNAMEN1 | |
| SCHEMBL1875162 | 0.80 | AKT1 (0.59) | CYP1B1ALDH1A1HTTLMNAMEN1 | |
| SCHEMBL10498659 | 0.76 | CYP1B1 (0.55) | CA1CA2KRASCYP1B1CTSL | |
| SCHEMBL11664896 | 0.75 | CYP1B1 (0.58) | CA1CA2KRASCYP1B1CTSL | |
| SCHEMBL28755492 | 0.74 | CYP1B1 (0.56) | CA1CA2KRASCYP1B1CTSL | |
| SCHEMBL10405641 | 0.74 | ALDH1A1 (0.67) | CYP1B1ALDH1A1HTTLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4510140-A | HYPOTENSIVE AGENTS; ANTHIHISTAMINES; ANALGESICS; SEDATIVES | RECORDATI S.A. (CH) | 1985-04-09 | — | — | US | disclosed |
| EP-0074768-A2 | Alkanoylanilides | RECORDATI S.A. CHEMICAL and PHARMACEUTICAL COMPANY (CH) | 1983-03-23 | — | — | EP | disclosed |