Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.33 |
| ▸ | HTR2C | P28335 | 6/20 | 0.33 |
| ▸ | HTR2B | P41595 | 6/20 | 0.33 |
| ▸ | HRH3 | Q9Y5N1 | 5/20 | 0.33 |
| ▸ | PRCP | P42785 | 2/20 | 0.33 |
| ▸ | IDO1 | P14902 | 1/20 | 0.33 |
| ▸ | TDO2 | P48775 | 1/20 | 0.33 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR1B | P28222 | 2/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 1/20 | 0.30 |
| ▸ | ACHE | P22303 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28401867 | 0.83 | HTR2A (0.34) | HTR2AHTR2CHTR2BHRH3PRCP | |
| SCHEMBL28408174 | 0.81 | HTR1D (0.33) | HTR2AHTR2CHTR2BHRH3HTR1D | |
| SCHEMBL7164210 | 0.78 | PRCP (0.36) | HTR2AHTR2CHTR2BHRH3PRCP | |
| SCHEMBL28369346 | 0.76 | SIGMAR1 (0.33) | BCHEACHE | |
| SCHEMBL2806120 | 0.74 | HTR2A (0.33) | HTR2AHTR2CHTR2BHRH3PRCP | |
| SCHEMBL5331264 | 0.73 | PTGDR2 (0.36) | HTR2AHTR2CHTR2BHRH3PRCP | |
| Hydrochloric Acid SCHEMBL6567139 | 0.72 | CYP11B1 (0.34) | CYP11B1CYP11B2 | |
| Hydrochloric Acid SCHEMBL6890250 | 0.72 | CYP11B1 (0.32) | HTR1DHTR1BCYP11B1CYP11B2 | |
| SCHEMBL1452158 | 0.72 | HTR2A (0.39) | HTR2AHTR2CHTR2BCYP11B1CYP11B2 | |
| SCHEMBL8648643 | 0.71 | PTGDR2 (0.33) | PRCPIDO1TDO2HTR1DHTR1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0133658-A2 | Flame retardant non-dripping polycarbonate compositions | GENERAL ELECTRIC COMPANY (US) | 1985-03-06 | — | — | EP | disclosed |