Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | TP53 | P04637 | 3/20 | 0.32 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26391494 | 0.86 | TSHR (0.44) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| E968 SCHEMBL29089122 | 0.85 | TSHR (0.38) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL1160696 | 0.83 | TDP1 (0.46) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4272239 | 0.83 | TDP1 (0.46) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4282348 | 0.82 | LMNA (0.40) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL21625758 | 0.82 | LMNA (0.40) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL16606863 | 0.82 | PDE4A (0.46) | LMNAPDE4ATSHRALDH1A1TP53 | |
| SCHEMBL27695890 | 0.81 | TSHR (0.44) | TSHRALDH1A1TP53HIF1ACYP3A4 | |
| SCHEMBL4271811 | 0.79 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1USP2 | |
| SCHEMBL4269101 | 0.79 | LMNA (0.38) | LMNAL3MBTL1PDE4ATDP1USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11779686-B2 | Coating for medical devices | PHENOX GMBH (DE) | 2023-10-10 | — | — | US | disclosed |
| US-4542137-A | NONEXPLOSIVE, CARDIOVASCULAR | DR. WILLMAR SCHWABE GMBH & CO. (DE) | 1985-09-17 | — | — | US | disclosed |
| US-4535158-A | CHEMICXAL INTERMEDIATES FOR CARDIOTONIC AGENTS | DR. WILLMAR SCHWABE GMBH & CO. | 1985-08-13 | — | — | US | disclosed |
| US-4413122-A | Optionally N-substituted aminodesoxy-1.4;3.6-dianhydrohexitol derivatives | FA. WILMAR SCHWABE GMBH & CO. (DE) | 1983-11-01 | — | — | US | disclosed |
| US-4363805-A | TREATMENT OF CORONARY DISEASE | FIRMA WILLMAR SCHWABE (DE) | 1982-12-14 | — | — | US | disclosed |