Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.54 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 1/20 | 0.37 |
| ▸ | HTR2C | P28335 | 1/20 | 0.37 |
| ▸ | HTR2B | P41595 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | P2RY1 | P47900 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9173964 | 0.84 | KMT2A (0.54) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL9482952 | 0.84 | KMT2A (0.54) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL7934892 | 0.81 | KMT2A (0.50) | KMT2AALDH1A1SLC6A2P2RY1MAPT | |
| SCHEMBL11993630 | 0.79 | KMT2A (0.66) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL1967959 | 0.79 | KMT2A (0.58) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL9362429 | 0.77 | KMT2A (0.59) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL11007881 | 0.75 | KMT2A (0.50) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL1538036 | 0.75 | KMT2A (0.69) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL5513970 | 0.74 | KMT2A (0.54) | KMT2AGAACYP1A2CYP2C9PKM | |
| SCHEMBL27094594 | 0.74 | KMT2A (0.54) | KMT2AGAACYP1A2CYP2C9PKM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517368-A | 2,3-Dichloro-5-iodopyridine and methods of making and using the same | THE DOW CHEMICAL COMPANY (US) | 1985-05-14 | — | — | US | disclosed |