SCHEMBL11034723

SCHEMBL11034723

[CH2]C(NC(=O)N(N=O)C(C)Cl)C(=O)OCC

nearest known ligand 0.32

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
CAD P27708 1/20 0.32
ALDH1A1 P00352 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28697232 0.72 ALDH1A1 (0.35) ALDH1A1
SCHEMBL4592519 0.68 ALDH1A1 (0.44) CADALDH1A1HPGD
SCHEMBL11445193 0.67 MGAM (0.39) CADALDH1A1
SCHEMBL10710775 0.64 MEN1 (0.35) ALDH1A1
SCHEMBL7671017 0.63
Acrylic Acid Ethyl Ester SCHEMBL28401233 0.62 TSHR (0.53) ALDH1A1HPGD
SCHEMBL26598542 0.62 CYP1A2 (0.52) ALDH1A1
SCHEMBL10983086 0.61 MGAM (0.41) CADALDH1A1
SCHEMBL5603 0.61
SCHEMBL17617672 0.61

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0117959-A2 Nitrosourea derivatives, process for their preparation and pharmaceutical compositions containing them ADIR (FR) 1984-09-12 EP disclosed