Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 1/20 | 0.53 |
| ▸ | TTR | P02766 | 1/20 | 0.53 |
| ▸ | PPOX | P50336 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CCR6 | P51684 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.41 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.39 |
| ▸ | AKR1C4 | P17516 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 1/20 | 0.39 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.39 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 5/20 | 0.38 |
| ▸ | MASP2 | O00187 | 1/20 | 0.37 |
| ▸ | F2 | P00734 | 1/20 | 0.37 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11108041 | 0.75 | TDP1 (0.61) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL11034743 | 0.74 | TDP1 (0.53) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL9576842 | 0.73 | TDP1 (0.59) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL8605506 | 0.73 | TTR (0.67) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL25027280 | 0.72 | GAA (0.45) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL31053862 | 0.72 | GAA (0.45) | TDP1MEN1KMT2AMAPTLMNA | |
| SCHEMBL11059316 | 0.72 | TDP1 (0.57) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10541909 | 0.71 | TDP1 (0.56) | TDP1MEN1TTRPPOXKMT2A | |
| SCHEMBL10598144 | 0.71 | TDP1 (0.74) | TDP1MEN1TTRPPOXKMT2A | |
| Acifluorfen SCHEMBL3228873 | 0.70 | TDP1 (1.00) | TDP1MEN1TTRPPOXKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4517010-A | 2-Nitro-5(substituted-phenoxy) benzoyl derivatives as herbicides | RHONE-POULENC INC. (US) | 1985-05-14 | — | — | US | disclosed |