Acifluorfen

Acifluorfen

SCHEMBL3228873

O=C(O)c1cc(Oc2ccc(C(F)(F)F)cc2Cl)ccc1[N+](=O)[O-]

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TDP1 Q9NUW8 3/20 1.00
MEN1 O00255 1/20 1.00
TTR P02766 1/20 1.00
PPOX P50336 1/20 1.00
KMT2A Q03164 1/20 1.00
FFAR1 O14842 5/20 0.53
PYGL P06737 1/20 0.50
AKR1B1 P15121 1/20 0.50
AKR1C4 P17516 1/20 0.50
AKR1C3 P42330 1/20 0.50
AKR1C2 P52895 1/20 0.50
AKR1C1 Q04828 1/20 0.50
MRGPRX4 Q96LA9 5/20 0.47
LMNA P02545 2/20 0.47
MAPT P10636 2/20 0.47
POLB P06746 1/20 0.47
CCR6 P51684 1/20 0.47
NPSR1 Q6W5P4 1/20 0.47
GPR55 Q9Y2T6 1/20 0.47
HPGD P15428 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acifluorfen SCHEMBL29448829 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL38929 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8028079 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL29445767 1.00 TDP1 (1.00) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL1830812 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL10556004 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL3690938 0.99 TDP1 (0.98) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL10542053 0.96 TDP1 (0.92) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8936622 0.95 TDP1 (0.90) TDP1MEN1TTRPPOXKMT2A
Acifluorfen SCHEMBL8028082 0.95 TDP1 (0.90) TDP1MEN1TTRPPOXKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 85 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12173301-B2 Weed control methods and related compositions and plants SYNGENTA CROP PROTECTION AG (CH) 2024-12-24 US claimed
EP-3599857-B1 HERBICIDAL MIXTURES BAYER AG (DE) 2023-08-23 EP claimed
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION Generic Crop Science LLC (US) 2023-01-05 US claimed
US-20220403406-A1 WEED CONTROL METHODS AND RELATED COMPOSITIONS AND PLANTS SYNGENTA CROP PROTECTION AG (CH) 2022-12-22 US claimed
EP-4054319-A1 WEED CONTROL METHODS AND RELATED COMPOSITIONS AND PLANTS Syngenta Crop Protection AG (CH) 2022-09-14 EP claimed
EP-3973063-A2 COMPOSITIONS AND METHODS FOR WEED CONTROL Syngenta Crop Protection AG (CH) 2022-03-30 EP claimed
EP-0496608-B1 Substituted pyridinesulfonamide compound or its salt, process for preparing the same, and herbicide containing the same ISHIHARA SANGYO KAISHA (JP) 1995-09-20 EP claimed
EP-0304409-B1 5-HETEROCYCLIC-SUBSTITUTED OXAZOLIDINE HALOACETAMIDES MONSANTO CO (US) 1992-10-28 EP claimed
EP-0080312-B1 THE PREPARATION OF CERTAIN DIPHENYL ETHERS ESPECIALLY 5-(4-TRIFLUOROMETHYLPHENOXY)- AND 5-(2-HALO-4-TRIFLUOROMETHYLPHENOXY)-2-NITROBENZOIC ACID AND SALTS AND ESTERS AND AMIDES ROHM AND HAAS COMPANY (US) 1985-05-29 EP claimed
EP-0040898-B1 2-NITRO-5-(SUBSTITUTED-PHENOXY) BENZOATE ESTERS OF ALPHA-HYDROXYALKANOATES AND METHODS OF USING SAME AS HERBICIDES RHONE-POULENC AGROCHIMIE (FR) 1985-01-16 EP claimed
US-4424393-A Process of preparation of substituted diphenyl ethers PPG INDUSTRIES, INC. (US) 1984-01-03 US claimed
JP-5025005-A None JP disclosed
US-12495798-B2 Nicotinamide compound and herbicidal composition comprising compound KOREA RESEARCH INSTITUTE OF CHEMICAL TECHNOLOGY (KR) 2025-12-16 US disclosed
EP-4651718-A1 METHODS OF CONTROLLING UNDESIRABLE PLANTS WITH PPO HERBICIDES AND COMBINATIONS IN HERBICIDE TOLERANT CROP PLANTS BASF Agro B.V. (NL) 2025-11-26 EP disclosed
US-12364263-B2 Low volatility herbicidal compositions MONSANTO TECHNOLOGY LLC (US) 2025-07-22 US disclosed
US-4311515-A Substituted diphenyl ethers having herbicidal activity PPG INDUSTRIES, INC. (US) 1982-01-19 US disclosed
US-4220468-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1980-09-02 US disclosed
US-4209318-A Herbicidal esters of 4-trifluoromethyl-3-carboxamido-4-nitro diphenyl ethers ROHM AND HAAS COMPANY (US) 1980-06-24 US disclosed
US-4093446-A Herbicidal 4-trifluoromethyl-4-nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1978-06-06 US disclosed
US-4063929-A Herbicidal 4-trifluoromethyl-4'nitrodiphenyl ethers ROHM AND HAAS COMPANY (US) 1977-12-20 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230000079-A1 COMBINATION COMPRISING A TRIKETONE HERBICIDE AND A DIPHENYLETHER HERBICIDE, AND A METHOD FOR MAKING AND USING THE COMBINATION DDT, TDO2, DNTT TDP1 289/4885MEN1 4740/4885TTR 543/4885
US-20220403406-A1 WEED CONTROL METHODS AND RELATED COMPOSITIONS AND PLANTS NOTUM, LYPLA2, LYPLA1 TDP1 779/4885MEN1 4884/4885TTR 1034/4885
US-12495798-B2 Nicotinamide compound and herbicidal composition comprising compound NAMPT, SIRT1, SIRT6 TDP1 2728/4885MEN1 3790/4885TTR 4159/4885
US-12173301-B2 Weed control methods and related compositions and plants NOTUM, LYPLA2, LYPLA1 TDP1 779/4885MEN1 4884/4885TTR 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.