Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.42 |
| ▸ | SLC2A2 | P11168 | 1/20 | 0.42 |
| ▸ | SLC2A3 | P11169 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 3/20 | 0.37 |
| ▸ | TSHR | P16473 | 3/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.36 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23996463 | 0.78 | ALDH1A1 (0.57) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL11312761 | 0.67 | ALDH1A1 (0.50) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL28005761 | 0.65 | HPGD (0.56) | ALDH1A1HPGDCYP1A2CYP3A4CYP2C19 | |
| SCHEMBL21851665 | 0.65 | ALDH1A1 (0.51) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL21851661 | 0.65 | ALDH1A1 (0.51) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL21851664 | 0.64 | ALDH1A1 (0.48) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL16179017 | 0.63 | HPGD (0.50) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL21851662 | 0.63 | DAPK1 (0.54) | SLC2A1SLC2A2SLC2A3ALDH1A1HPGD | |
| SCHEMBL11773963 | 0.62 | TP53 (0.49) | ALDH1A1HPGDMAPTSMN1; SMN2NPC1 | |
| SCHEMBL29487316 | 0.62 | MAPT (0.56) | ALDH1A1HPGDMAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59062595-A | — | — | None | — | — | JP | disclosed |
| JP-S5962595-A | 3,5,7-TRISUBSTITUTED-TRIAZOLOPYRIMIDINE DERIVATIVE AND ITS PREPARATION | SS PHARMACEUT CO LTD | 1984-04-10 | — | — | JP | disclosed |