Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CAPN1 | P07384 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HDAC3 | O15379 | 4/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 4/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 4/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.35 |
| ▸ | HDAC8 | Q9BY41 | 4/20 | 0.35 |
| ▸ | HDAC6 | Q9UBN7 | 4/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 3/20 | 0.35 |
| ▸ | NCOR2 | Q9Y618 | 1/20 | 0.33 |
| ▸ | TRHR | P34981 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.33 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.33 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.33 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.33 |
| ▸ | MME | P08473 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10823690 | 0.84 | TRHR (0.52) | TRHR | |
| SCHEMBL11005409 | 0.84 | TRHR (0.52) | TRHR | |
| SCHEMBL11009264 | 0.83 | TRHR (0.38) | TRHR | |
| SCHEMBL6026783 | 0.76 | TRHR (0.46) | TRHR | |
| SCHEMBL6026780 | 0.76 | TRHR (0.46) | TRHR | |
| SCHEMBL29405912 | 0.76 | TRHR (0.46) | TRHR | |
| SCHEMBL27869228 | 0.76 | TRHR (0.46) | TRHR | |
| SCHEMBL7271889 | 0.74 | MAPT (0.42) | TDP1HDAC3HDAC1HDAC10HDAC11 | |
| SCHEMBL18048894 | 0.73 | CTSC (0.45) | TSHRTRHRMMEREN | |
| SCHEMBL18048893 | 0.73 | CTSC (0.45) | TSHRTRHRMMEREN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0134582-A2 | Novel peptides and process for preparing the same and pharmaceutical composition | Tanabe Seiyaku Co., Ltd. (JP) | 1985-03-20 | — | — | EP | disclosed |