Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | CA9 | Q16790 | 3/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | AKT1 | P31749 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 2/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10848509 | 1.00 | MAPT (0.36) | MAPTALDH1A1KDM4ENPC1HTT | |
| SCHEMBL11001269 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10850250 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL11036888 | 0.86 | ALDH1A1 (0.42) | MAPTALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL9763025 | 0.86 | KDM4E (0.48) | MAPTALDH1A1KDM4ENPC1CA1 | |
| SCHEMBL10836053 | 0.85 | EDNRA (0.42) | MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL11035297 | 0.85 | EDNRA (0.42) | MAPTALDH1A1KDM4ENPC1 | |
| SCHEMBL10848254 | 0.84 | SMN1; SMN2 (0.47) | MAPTALDH1A1HTTNPSR1SMN1; SMN2 | |
| SCHEMBL9763397 | 0.81 | KDM4E (0.46) | MAPTALDH1A1KDM4ENPC1HTT | |
| SCHEMBL11035098 | 0.80 | EDNRA (0.39) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0148498-A1 | Sulfonylguanidine derivatives | NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) | 1985-07-17 | — | — | EP | disclosed |