Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RECQL | P46063 | 1/20 | 0.43 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NNMT | P40261 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10847771 | 0.87 | HTT (0.41) | SMN1; SMN2ALDH1A1MEN1KMT2APOLB | |
| SCHEMBL27290280 | 0.81 | SMN1; SMN2 (0.64) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 | |
| SCHEMBL11037206 | 0.76 | CYP1A2 (0.38) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 | |
| SCHEMBL28247621 | 0.75 | CYP1A2 (0.36) | SMN1; SMN2ALDH1A1CYP1A2POLBLMNA | |
| SCHEMBL11066173 | 0.74 | TSHR (0.35) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 | |
| SCHEMBL10847815 | 0.74 | SMN1; SMN2 (0.48) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 | |
| SCHEMBL10848328 | 0.74 | MEN1 (0.35) | SMN1; SMN2TSHRALDH1A1MEN1KMT2A | |
| SCHEMBL8540620 | 0.73 | CYP1A2 (0.43) | SMN1; SMN2TSHRALDH1A1CYP1A2KMT2A | |
| SCHEMBL2238434 | 0.71 | SMN1; SMN2 (0.49) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 | |
| SCHEMBL9735397 | 0.71 | SMN1; SMN2 (0.69) | SMN1; SMN2TSHRALDH1A1CYP1A2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0141199-A2 | N-substituted sulfamoyl chlorides and preparation thereof | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1985-05-15 | — | — | EP | claimed |