Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.69 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | TSHR | P16473 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10867034 | 0.92 | SMN1; SMN2 (0.67) | SMN1; SMN2KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9591445 | 0.90 | KDM4E (0.58) | SMN1; SMN2KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9741957 | 0.88 | SMN1; SMN2 (0.55) | SMN1; SMN2KDM4ETSHRMEN1KMT2A | |
| SCHEMBL10867587 | 0.85 | SMN1; SMN2 (0.56) | SMN1; SMN2KDM4ETSHRMEN1KMT2A | |
| SCHEMBL10498917 | 0.81 | KDM4E (0.54) | SMN1; SMN2KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9586844 | 0.80 | SMN1; SMN2 (0.42) | SMN1; SMN2KDM4ETSHRMEN1KMT2A | |
| SCHEMBL9478178 | 0.77 | KDM4E (0.50) | SMN1; SMN2KDM4EMEN1KMT2ACYP1A2 | |
| SCHEMBL9743094 | 0.77 | CA1 (0.47) | SMN1; SMN2MEN1KMT2ANPSR1ALDH1A1 | |
| SCHEMBL9588686 | 0.76 | CA1 (0.48) | SMN1; SMN2KDM4EMEN1KMT2AGAA | |
| SCHEMBL9740917 | 0.75 | SMN1; SMN2 (0.38) | SMN1; SMN2TSHRMEN1KMT2ACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5092917-A | HERBICIDAL AMINOGUANIDINOAZINES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-03-03 | — | — | US | claimed |
| US-5091529-A | HERBICIDAL SUBSTITUTED SULPHONYLAMINOAZOLES | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-25 | — | — | US | disclosed |
| US-5021082-A | Pre=and postemergent | BAYER AKTIENGESELLSCHAFT (DE) | 1991-06-04 | — | — | US | disclosed |
| US-4941912-A | Herbicidal substituted sulphonylaminoazoles | BAYER AKTIENGESELLSCHAFT (DE) | 1990-07-17 | — | — | US | disclosed |