Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | GLS | O94925 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.31 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 2/20 | 0.31 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29144461 | 0.76 | LMNA (0.43) | LMNAMAPK1CES2CES1HPGD | |
| Phenol SCHEMBL28156977 | 0.75 | CA12 (0.37) | LMNACES2KMT2A | |
| SCHEMBL4395716 | 0.75 | LMNA (0.36) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL8758002 | 0.71 | LMNA (0.41) | LMNAMAPK1CES2CES1HPGD | |
| Pyrrole SCHEMBL17760475 | 0.70 | LMNA (0.37) | LMNAMAPK1CES2CES1HPGD | |
| SCHEMBL6752183 | 0.65 | MEN1 (0.30) | KMT2A | |
| SCHEMBL123293 | 0.64 | MAOB (0.33) | — | |
| Mandelic Acid SCHEMBL388004 | 0.64 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL30437233 | 0.64 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD | |
| Mandelic Acid SCHEMBL30015054 | 0.64 | LMNA (0.62) | LMNAMAPK1CES2CES1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0082117-B1 | CHROMIUM COMPLEXES OF POLYAZO DYESTUFFS | CIBA-GEIGY AG (CH) | 1985-04-10 | — | — | EP | disclosed |