Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 2/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.39 |
| ▸ | ERN1 | O75460 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.35 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | STAT3 | P40763 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035931 | 1.00 | GPR35 (0.41) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL11034340 | 0.87 | MAPT (0.53) | MAPTKDM4ECA12SOS1ALDH1A1 | |
| SCHEMBL11034335 | 0.87 | MAPT (0.53) | MAPTKDM4ECA12SOS1ALDH1A1 | |
| SCHEMBL7298558 | 0.81 | TSHR (0.44) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL10414316 | 0.81 | TSHR (0.44) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL11006035 | 0.78 | TSHR (0.50) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL7298528 | 0.78 | TSHR (0.50) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL9422617 | 0.75 | GPR35 (0.53) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL1174499 | 0.72 | MAPT (0.73) | GPR35TSHRMAPTERN1KDM4E | |
| SCHEMBL27935920 | 0.70 | ERN1 (0.65) | GPR35TSHRMAPTERN1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4506078-A | 7-AMINOINDOLE PHOTOGRAPHIC DYES | HOFFMANN-LA ROCHE INC. (US) | 1985-03-19 | — | — | US | disclosed |