Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | RAB9A | P51151 | 4/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | BRD4 | O60885 | 1/20 | 0.50 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | MEN1 | O00255 | 3/20 | 0.47 |
| ▸ | MET | P08581 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | IL2 | P60568 | 1/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663087 | 0.94 | RAB9A (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL8659238 | 0.90 | RAB9A (0.65) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL11012517 | 0.88 | RAB9A (0.55) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL8656265 | 0.88 | RAB9A (0.49) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL11096424 | 0.84 | RAB9A (0.61) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL11011327 | 0.82 | ATM (0.51) | SMN1; SMN2RAB9ANPC1DEGS1KMT2A | |
| SCHEMBL11176913 | 0.82 | IL2 (0.47) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL11237470 | 0.81 | MEN1 (0.51) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL8672283 | 0.81 | MEN1 (0.50) | SMN1; SMN2RAB9ANPC1ALDH1A1PKM | |
| SCHEMBL11015466 | 0.80 | RAB9A (0.55) | RAB9ANPC1DEGS1KMT2AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4405552-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-09-20 | — | — | US | claimed |
| US-4508722-A | 1-Benzoyl-3-(arylpyridyl)urea compounds | ELI LILLY AND COMPANY (US) | 1985-04-02 | — | — | US | disclosed |
| US-4405552-A | INSECTICIDES | ELI LILLY AND COMPANY (US) | 1983-09-20 | — | — | US | disclosed |
| EP-0060071-A1 | Improvements in or relating to 1-benzoyl-3-(arylpyridyl)urea compounds | ELI LILLY AND COMPANY (US) | 1982-09-15 | — | — | EP | disclosed |