Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 14/20 | 0.49 |
| ▸ | SLC6A4 | P31645 | 14/20 | 0.49 |
| ▸ | SLC6A3 | Q01959 | 13/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020711 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL12363801 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL21081146 | 0.82 | SLC6A2 (0.56) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL12363776 | 0.78 | SLC6A2 (0.54) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL19010153 | 0.75 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL19010164 | 0.75 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL19010163 | 0.75 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL4332166 | 0.75 | SLC6A2 (0.51) | SLC6A2SLC6A4SLC6A3CYP2D6 | |
| SCHEMBL6758153 | 0.74 | BCHE (0.59) | — | |
| SCHEMBL22582254 | 0.74 | GRM2 (0.41) | CYP2D6ALDH1A1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4537895-A | 4-PHENYL, 8-CARBONYLAMINO DERIVATIVES FOR CENTRAL NERVOUS SYSTEM DISORDERS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1985-08-27 | — | — | US | claimed |
| US-4537895-A | 4-PHENYL, 8-CARBONYLAMINO DERIVATIVES FOR CENTRAL NERVOUS SYSTEM DISORDERS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1985-08-27 | — | — | US | disclosed |
| US-4537895-A | 4-PHENYL, 8-CARBONYLAMINO DERIVATIVES FOR CENTRAL NERVOUS SYSTEM DISORDERS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1985-08-27 | — | — | US | disclosed |