SCHEMBL6758153

SCHEMBL6758153

CCCCCC1CCc2ccccc21

nearest known ligand 0.62

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
BCHE P06276 1/20 0.59
DRD2 P14416 1/20 0.49
HTR6 P50406 1/20 0.47
MTNR1A P48039 1/20 0.47
MTNR1B P49286 1/20 0.47
SIGMAR1 Q99720 3/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28989835 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL27515867 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL28989836 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL19259383 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL28256253 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL9571237 0.98 BCHE (0.58) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL29903265 0.97 BCHE (0.56) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL27838111 0.95 BCHE (0.60) BCHEDRD2HTR6MTNR1AMTNR1B
SCHEMBL6689910 0.90 SIGMAR1 (0.55) BCHESIGMAR1
SCHEMBL30364914 0.90 SIGMAR1 (0.55) BCHESIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-109071439-B Process for preparing 4-aminoindane derivatives and related aminoindane amides I-F产品协作基金会 2022-07-15 CN claimed
US-11148995-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides STICHTING I-F PRODUCT COLLABORATION (NL) 2021-10-19 US claimed
US-20200231533-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES FMC IP TECHNOLOGY GMBH (CH) 2020-07-23 US claimed
US-10640454-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides STICHTING I-F PRODUCT COLLABORATION (NL) 2020-05-05 US claimed
EP-3442944-B1 PROCESS FOR THE PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES STICHTING I F PRODUCT COLLABORATION (NL) 2020-04-15 EP claimed
US-20190119195-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES FMC IP TECHNOLOGY GMBH (CH) 2019-04-25 US claimed
EP-3442944-A1 PROCESS FOR THE PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES Stichting I-F Product Collaboration (NL) 2019-02-20 EP claimed
WO-2017178868-A1 PROCESS FOR THE PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES STICHTING I-F PRODUCT COLLABORATION (NL) 2017-10-19 WO claimed
CN-1751031-A HIV replication inhibiting pyrimidines and triazines TIBOTEC PHARM LTD (IE) 2006-03-22 CN claimed
US-11959010-B2 Heat storage composition, heat storage member, electronic device, and manufacturing method of heat storage member FUJIFILM CORPORATION (JP) 2024-04-16 US disclosed
US-11851388-B2 Compound of 1-acetyl-6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline FMC AGRO SINGAPORE PTE. LTD. (SG) 2023-12-26 US disclosed
CN-116354182-A Reel body container and reel body 富士胶片株式会社 2023-06-30 CN disclosed
CN-116354184-A Rolling body 富士胶片株式会社 2023-06-30 CN disclosed
CN-113727849-B Heat storage member 富士胶片株式会社 2023-06-30 CN disclosed
US-6653307-B2 Such as N-(4-chlorobenzyl)-6-(4-morpholinylmethyl)-4-oxo-1-phenyl-1,4-dihydro-3-quinolinecarboxamide for treatment of herpes virus; viral DNA polymerase inhibitors PHARMACIA & UPJOHN COMPANY 2003-11-25 US disclosed
CN-1432001-A 1-aryl-4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents UPJOHN CO (US) 2003-07-23 CN disclosed
EP-1292575-A2 1-ARYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 2003-03-19 EP disclosed
US-20020103220-A1 1-Aryl-4oxo-1,4-Dihydro-3-quinolinecarboxamides as antiviral agents PHARMACIA & UPJOHN COMPANY 2002-08-01 US disclosed
WO-2001098275-A2 1-ARYL-4-OXO-1,4-DIHYDRO-3-QUINOLINECARBOXAMIDES AS ANTIVIRAL AGENTS PHARMACIA & UPJOHN COMPANY (US) 2001-12-27 WO disclosed
EP-0114385-B1 ELECTRICAL INSULATING OIL AND OIL-FILLED ELECTRICAL APPLIANCES NIPPON PETROCHEMICALS COMPANY, LIMITED (JP) 1987-08-05 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11851388-B2 Compound of 1-acetyl-6-fluoro-2,2,4-trimethyl-1,2,3,4-tetrahydroquinoline HDAC3, HDAC6, KAT2A BCHE 2390/4885DRD2 2234/4885HTR6 462/4885
US-10640454-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides AADAT, ALDH7A1, AAAS BCHE 539/4885DRD2 160/4885HTR6 257/4885
US-20190119195-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE DERIVATIVES AND RELATED AMINOINDANE AMIDES ALDH7A1, AADAT, AASDHPPT BCHE 599/4885DRD2 164/4885HTR6 326/4885
US-11148995-B2 Processes for preparation of 4-aminoindane compounds and related aminoindane amides AADAT, ALDH7A1, AAAS BCHE 474/4885DRD2 287/4885HTR6 428/4885
US-20020103220-A1 1-Aryl-4oxo-1,4-Dihydro-3-quinolinecarboxamides as antiviral agents ZC3HAV1, IRF3, ZC3HAV1L BCHE 4286/4885DRD2 4470/4885HTR6 4037/4885
US-20200231533-A1 PROCESSES FOR PREPARATION OF 4-AMINOINDANE COMPOUNDS AND RELATED AMINOINDANE AMIDES AADAT, ALDH7A1, AAAS BCHE 474/4885DRD2 287/4885HTR6 428/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.