SCHEMBL1103640

SCHEMBL1103640

CC1(C)c2ccccc2-c2ccc(-c3ccc4c(-c5ccc(-c6ccccc6)cc5)c5cnccc5c(-c5ccc(-c6ccccc6)cc5)c4c3)cc21

nearest known ligand 0.40

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
PDK2 Q15119 10/20 0.40
TNF P01375 1/20 0.35
PIK3CA P42336 1/20 0.34
MAPK10 P53779 1/20 0.34
IMPDH2 P12268 1/20 0.34
PIK3CD O00329 1/20 0.33
ALOX5 P09917 1/20 0.33
MKNK1 Q9BUB5 1/20 0.33
DGAT2 Q96PD7 1/20 0.32
MAP2 P11137 1/20 0.32
TDP2 O95551 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1103638 0.99 PDK2 (0.41) PDK2TNFPIK3CAMAPK10IMPDH2
SCHEMBL1103678 0.98 PDK2 (0.39) PDK2TNFPIK3CAMAPK10IMPDH2
SCHEMBL1103624 0.98 PDK2 (0.40) PDK2TNFPIK3CAMAPK10IMPDH2
SCHEMBL1103641 0.95 PDK2 (0.38) PDK2TNFMAPK10PIK3CDALOX5
SCHEMBL1102799 0.95 PDK2 (0.42) PDK2TNFPIK3CAMAPK10PIK3CD
SCHEMBL1103644 0.94 PDK2 (0.40) PDK2TNFPIK3CDTDP2
SCHEMBL1102593 0.93 PDK2 (0.42) PDK2TNFPIK3CDALOX5MAP2
SCHEMBL1102629 0.93 PDK2 (0.39) PDK2TNFMAPK10PIK3CDALOX5
SCHEMBL1102536 0.93 PDK2 (0.43) PDK2TNFPIK3CD
SCHEMBL1103681 0.92 CYP11B2 (0.38) PDK2TNFMAPK10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-8153279-B2 Organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2012-04-10 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same GRACEL DISPLAY INC. (KR) 2010-02-11 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100033083-A1 Novel organic electroluminescent compounds and organic electroluminescent device using the same ORMDL3, OCIAD2, OCIAD1 PDK2 1930/4885TNF 3803/4885PIK3CA 3393/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.