Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.38 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.32 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13706803 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL769036 | 1.00 | ALDH1A1 (0.40) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL6167486 | 0.86 | ALDH1A1 (0.37) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL14279226 | 0.82 | POLB (0.42) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL27880913 | 0.78 | ALDH1A1 (0.41) | ALDH1A1TDP1CYP2C9 | |
| Trimethylammonium SCHEMBL27871906 | 0.77 | ALDH1A1 (0.42) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL365556 | 0.77 | MAPT (0.40) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL841854 | 0.76 | POLB (0.41) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL15075199 | 0.76 | POLB (0.41) | ALDH1A1POLBMEN1KMT2ATDP1 | |
| SCHEMBL841855 | 0.76 | POLB (0.41) | ALDH1A1POLBMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0029443-B1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LIMITED (AU) | 1984-05-16 | — | — | EP | claimed |
| EP-0029443-A4 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-09-21 | — | — | EP | claimed |
| EP-0029443-A1 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-06-03 | — | — | EP | claimed |
| WO-1980002687-A1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LTD (AU) | 1980-12-11 | — | — | WO | claimed |
| US-9403827-B2 | Substituted purinone compounds | NOVARTIS AG (CH) | 2016-08-02 | — | — | US | disclosed |
| US-20150353551-A1 | SUBSTITUTED PURINONE COMPOUNDS | NOVARTIS AG (CH) | 2015-12-10 | — | — | US | disclosed |
| EP-0029443-B1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LIMITED (AU) | 1984-05-16 | — | — | EP | disclosed |
| US-4447475-A | MIXING DISPERSION OF PARTICLES IN CROSSLINKED STYRENE POLYMER MATRIX WITH DISPERSANT AND SUSPENSION STABILIZER | ICI AUSTRALIA LIMITED (AU) | 1984-05-08 | — | — | US | disclosed |
| EP-0029443-A4 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-09-21 | — | — | EP | disclosed |
| EP-0029443-A1 | PROCESS FOR COMPOSITE POLYMER BEADS. | ICI AUSTRALIA LTD (AU) | 1981-06-03 | — | — | EP | disclosed |
| WO-1980002687-A1 | PROCESS FOR COMPOSITE POLYMER BEADS | ICI AUSTRALIA LTD (AU) | 1980-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150353551-A1 | SUBSTITUTED PURINONE COMPOUNDS | MDM2, MDM4, TP53 | ALDH1A1 698/4885POLB 446/4885MEN1 225/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.