Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.57 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.32 |
| ▸ | AR | P10275 | 2/20 | 0.31 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14175783 | 0.82 | LMNA (0.46) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL14161808 | 0.82 | LMNA (0.46) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL23588970 | 0.82 | LMNA (0.46) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL21882378 | 0.80 | LMNA (0.48) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL13377142 | 0.80 | LMNA (0.48) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL14495177 | 0.80 | LMNA (0.48) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL26290985 | 0.77 | LMNA (0.38) | LMNACYP2C9MEN1CYP2D6KMT2A | |
| SCHEMBL22408562 | 0.77 | LMNA (0.41) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL22408564 | 0.77 | LMNA (0.41) | LMNACYP2C9CHRM2CHRM1CHRM3 | |
| SCHEMBL23262204 | 0.75 | LMNA (0.57) | LMNACYP2C9CHRM2CHRM1CHRM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0042365-B1 | SALTS OF ENDO-8-METHYL-8-SYN-ALKYL-8-AZONIABICYCLO-(3.2.1)-OCTANE-3-ALKYLCARBOXYLATES, PROCESS FOR THEIR PREPARATION AND THERAPEUTIC COMPOSITIONS CONTAINING THEM | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1984-09-12 | — | — | EP | disclosed |
| US-4411902-A | ANTISPASMODICS | VALEAS S.P.A. (IT) | 1983-10-25 | — | — | US | disclosed |
| EP-0042365-A1 | Salts of endo-8-methyl-8-syn-alkyl-8-azoniabicyclo-(3.2.1)-octane-3-alkylcarboxylates, process for their preparation and therapeutic compositions containing them | VALEAS S.p.A. INDUSTRIA CHIMICA E FARMACEUTICA (IT) | 1981-12-23 | — | — | EP | disclosed |