Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | CA5A | P35218 | 1/20 | 0.46 |
| ▸ | TLR3 | O15455 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 2/20 | 0.43 |
| ▸ | HTR2B | P41595 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CNR1 | P21554 | 1/20 | 0.37 |
| ▸ | CNR2 | P34972 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7608955 | 0.87 | MAPT (0.46) | KDM4EALDH1A1CA2CA5ATLR3 | |
| SCHEMBL9748880 | 0.83 | KDM4E (0.46) | KDM4EALDH1A1CA2CA5AMAPT | |
| SCHEMBL9516408 | 0.83 | KDM4E (0.43) | KDM4EALDH1A1CA2CA5ATLR3 | |
| SCHEMBL10585397 | 0.82 | KDM4E (0.45) | KDM4EALDH1A1CA2CA5AMAPT | |
| SCHEMBL3318162 | 0.82 | CFTR (0.46) | TLR3 | |
| SCHEMBL3318159 | 0.82 | CFTR (0.46) | TLR3 | |
| SCHEMBL31085042 | 0.82 | TRPV1 (0.43) | ALDH1A1TLR3HIF1AMEN1KMT2A | |
| Hydrochloric Acid SCHEMBL17708952 | 0.81 | KDM4E (0.44) | KDM4EALDH1A1CA2CA5AMAPT | |
| SCHEMBL9749322 | 0.80 | KDM4E (0.43) | KDM4EALDH1A1TLR3MAPTTMEM97 | |
| SCHEMBL31260267 | 0.80 | MAPT (0.47) | KDM4EALDH1A1TLR3MAPTHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0129636-A1 | Process for the preparation of chromen derivatives | ALKALOIDA VEGYéSZETI GYáR (HU) | 1985-01-02 | — | — | EP | disclosed |