SCHEMBL9516408

SCHEMBL9516408

CC(C)C1CC(C)(C)Oc2cc(O)ccc21

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.43
ALDH1A1 P00352 2/20 0.43
TMEM97 Q5BJF2 2/20 0.43
HTR2B P41595 1/20 0.43
SIGMAR1 Q99720 1/20 0.43
MAPT P10636 2/20 0.40
CA2 P00918 1/20 0.37
CA5A P35218 1/20 0.37
SMN1; SMN2 Q16637 2/20 0.37
TDP1 Q9NUW8 1/20 0.37
L3MBTL1 Q9Y468 1/20 0.37
MGAM O43451 1/20 0.36
TLR3 O15455 1/20 0.36
PTPN1 P18031 1/20 0.36
LMNA P02545 2/20 0.36
HIF1A Q16665 1/20 0.35
ALOX12 P18054 1/20 0.35
ESR1 P03372 1/20 0.35
ESR2 Q92731 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037376 0.83 KDM4E (0.46) KDM4EALDH1A1TMEM97HTR2BSIGMAR1
SCHEMBL9748880 0.80 KDM4E (0.46) KDM4EALDH1A1TMEM97HTR2BSIGMAR1
SCHEMBL10585397 0.78 KDM4E (0.45) KDM4EALDH1A1TMEM97HTR2BSIGMAR1
SCHEMBL12758286 0.78 TLR3 (0.31) ALDH1A1TLR3
SCHEMBL24090500 0.78 KMT2A (0.36) ALDH1A1SMN1; SMN2LMNA
SCHEMBL25515620 0.78 KMT2A (0.36) ALDH1A1SMN1; SMN2LMNA
SCHEMBL10847547 0.78 KMT2A (0.36) ALDH1A1SMN1; SMN2LMNA
Hydrochloric Acid SCHEMBL17708952 0.77 KDM4E (0.44) KDM4EALDH1A1TMEM97HTR2BSIGMAR1
SCHEMBL31545269 0.77 HSP90AA1 (0.33) ALDH1A1HTR2BMAPTTLR3LMNA
SCHEMBL9749322 0.76 KDM4E (0.43) KDM4EALDH1A1TMEM97HTR2BSIGMAR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0515388-B1 PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND KODAK LTD (GB) 1993-11-18 EP disclosed
EP-0515388-A1 PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND. KODAK LTD (GB) 1992-12-02 EP disclosed
WO-1991011749-A1 PHOTOGRAPHIC SILVER HALIDE MATERIALS CONTAINING A STABILISER COMPOUND KODAK LIMITED (GB) 1991-08-08 WO disclosed