Betanaphthol

Betanaphthol

SCHEMBL11037634

COc1ccccc1N.Oc1ccc2ccccc2c1

nearest known ligand 0.60

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.60
ADRA2B P18089 1/20 0.60
PTGS1 P23219 1/20 0.60
TDP1 Q9NUW8 1/20 0.60
CYP1A2 P05177 2/20 0.57
GAA P10253 2/20 0.53
RCE1 Q9Y256 1/20 0.53
ESR1 P03372 3/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
ESR2 Q92731 2/20 0.49
CDK5 Q00535 1/20 0.46
CDK5R1 Q15078 1/20 0.46
NPC1 O15118 1/20 0.45
HSP90AA1 P07900 1/20 0.45
RAB9A P51151 1/20 0.45
L3MBTL1 Q9Y468 1/20 0.45
CYP2A6 P11509 1/20 0.44
TLR8 Q9NR97 1/20 0.44
ABL1 P00519 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11494800 0.84 ALDH1A1 (0.67) ALDH1A1ADRA2BPTGS1TDP1GAA
Betanaphthol SCHEMBL454131 0.80 CYP1A2 (0.81) PTGS1TDP1CYP1A2ESR1MEN1
SCHEMBL9317358 0.78 ALDH1A1 (0.53) ALDH1A1ADRA2BPTGS1TDP1GAA
Phenol SCHEMBL11879604 0.78 ALDH1A1 (0.75) ALDH1A1ADRA2BPTGS1TDP1CYP1A2
Betanaphthol SCHEMBL10964729 0.78 CYP1A2 (0.59) ALDH1A1TDP1CYP1A2GAAESR1
SCHEMBL14598 0.78
SCHEMBL29390378 0.78
Betanaphthol SCHEMBL10802368 0.77 CYP1A2 (0.76) TDP1CYP1A2ESR1MEN1KMT2A
Betanaphthol SCHEMBL27401934 0.77 CYP1A2 (0.68) ALDH1A1TDP1CYP1A2GAARCE1
Betanaphthol SCHEMBL27598725 0.75 CYP1A2 (0.90) PTGS1TDP1CYP1A2ESR1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4536570-A DIRECT DYES;DYEING OF CELLULOSE THE HILTON-DAVIS CHEMICAL CO. (US) 1985-08-20 US disclosed
US-4379088-A N-Aminoalkylenesulfonamido substituted monoazo colorants STERLING DRUG INC. (US) 1983-04-05 US disclosed
US-4379089-A Polyaminoalkylenesulfonamidated disazo colorants STERLING DRUG INC. (US) 1983-04-05 US disclosed