SCHEMBL11037722

SCHEMBL11037722

C=C(C)C(=O)OC1CCC(C[Si](O[Si](C)(C)C)(O[Si](C)(C)C)O[Si](C)(C)C)CC1O

nearest known ligand 0.31

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11037782 0.90 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11073924 0.90 ALDH1A1 (0.31) ALDH1A1
SCHEMBL11036276 0.88
SCHEMBL11037969 0.85
SCHEMBL15941432 0.82
SCHEMBL11042432 0.82
SCHEMBL11043028 0.82
SCHEMBL11039929 0.82
SCHEMBL11039916 0.81
SCHEMBL11041050 0.80 MEN1 (0.30)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0115531-A1 SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM POLYMATIC INVESTMENT CORPORATION N.V. (AN) 1984-08-15 EP disclosed
US-4450264-A CROSSLINKED COPOLYMER OF A TRIS/TRIMETHYLSILOXY/SILYL ALKYL OR CYCLOHEXYL ACRYLATE; OXYGEN PERMEABILITY POLYMATIC INVESTMENT CORP., N.V. (NL) 1984-05-22 US disclosed
WO-1984000763-A1 SILOXANE-CONTAINING POLYMERS AND CONTACT LENSES THEREFROM POLYMATIC INVESTMENT CORP NV (NL) 1984-03-01 WO disclosed