Biphenyl

Biphenyl

SCHEMBL11037814

[KH].[KH].c1ccc(-c2ccccc2)cc1

nearest known ligand 0.90

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Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.90
MAPK1 P28482 2/20 0.56
TAAR1 Q96RJ0 2/20 0.56
CYP1A2 P05177 1/20 0.56
CYP3A4 P08684 1/20 0.56
HSD17B10 Q99714 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
NOTUM Q6P988 1/20 0.56
MMP3 P08254 1/20 0.56
BCL2L1 Q07817 1/20 0.56
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
ATM Q13315 1/20 0.50
SLC22A2 O15244 1/20 0.50
SLC22A1 O15245 1/20 0.50
SLC22A3 O75751 1/20 0.50
SLC6A4 P31645 1/20 0.50
MAOA P21397 1/20 0.47
NFKB1 P19838 1/20 0.47
NFKB2 Q00653 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Biphenyl SCHEMBL3888058 1.00 ALDH1A1 (0.90) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL11152513 0.95 ALDH1A1 (0.82) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL29008551 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL1358618 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL29560186 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL30629023 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
SCHEMBL30108088 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL2548048 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL164 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4
Biphenyl SCHEMBL4002609 0.95 ALDH1A1 (1.00) ALDH1A1MAPK1TAAR1CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4467123-A Process for the preparation of alkali metal diphenylates and free hydroxydiphenyls BAYER AKTIENGESELLSCHAFT (DE) 1984-08-21 US disclosed