Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 10/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | PREP | P48147 | 1/20 | 0.47 |
| ▸ | FAP | Q12884 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10653350 | 0.96 | ACE (0.50) | ACELMNAITGB3ITGB1ITGAV | |
| SCHEMBL10656626 | 0.84 | ACE (0.52) | ACELMNAITGB3ITGB1ITGAV | |
| SCHEMBL3472243 | 0.83 | ACE (0.60) | ACELMNAITGB3ITGB1ITGAV | |
| SCHEMBL11435575 | 0.81 | ACE (0.71) | ACEPREPFAPACE2 | |
| SCHEMBL3472327 | 0.81 | ACE (0.71) | ACEPREPFAPACE2 | |
| SCHEMBL29749309 | 0.81 | ACE (0.71) | ACEPREPFAPACE2 | |
| Arginine SCHEMBL10654662 | 0.80 | ACE (0.43) | ACELMNAACE2SMN1; SMN2 | |
| SCHEMBL18586364 | 0.79 | ELANE (0.61) | ACEITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL20484667 | 0.79 | ELANE (0.61) | ACEITGB3ITGB1ITGAVITGA5 | |
| SCHEMBL11104635 | 0.78 | ACE (0.55) | ACELMNAPREPFAPKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-59206343-A | — | — | None | — | — | JP | disclosed |
| JP-S59206343-A | PROLINE DERIVATIVE | OTSUKA PHARMACEUT FACTORY INC | 1984-11-22 | — | — | JP | disclosed |