Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 2/20 | 0.61 |
| ▸ | CCR1 | P32246 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | DGAT1 | O75907 | 2/20 | 0.50 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.49 |
| ▸ | ACE | P12821 | 5/20 | 0.48 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.48 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.48 |
| ▸ | ITGAV | P06756 | 1/20 | 0.48 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.48 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.48 |
| ▸ | CMA1 | P23946 | 1/20 | 0.47 |
| ▸ | THRB | P10828 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18586364 | 1.00 | ELANE (0.61) | ELANECCR1KMT2AMEN1DGAT1 | |
| SCHEMBL18586541 | 0.90 | ELANE (0.60) | ELANECCR1KMT2AMEN1DGAT1 | |
| SCHEMBL18619664 | 0.90 | ELANE (0.60) | ELANECCR1KMT2AMEN1EPHX2 | |
| SCHEMBL22209466 | 0.90 | ELANE (0.60) | ELANECCR1KMT2AMEN1EPHX2 | |
| SCHEMBL20484759 | 0.90 | ELANE (0.60) | ELANECCR1KMT2AMEN1DGAT1 | |
| SCHEMBL22209391 | 0.89 | ALDH1A1 (0.54) | ELANECCR1KMT2AMEN1CMA1 | |
| SCHEMBL22209390 | 0.89 | ALDH1A1 (0.54) | ELANECCR1KMT2AMEN1CMA1 | |
| SCHEMBL20484710 | 0.88 | DGAT1 (0.54) | ELANECCR1KMT2AMEN1DGAT1 | |
| SCHEMBL18621658 | 0.88 | DGAT1 (0.54) | ELANECCR1KMT2AMEN1DGAT1 | |
| SCHEMBL7309861 | 0.87 | ELANE (0.62) | ELANECCR1KMT2AMEN1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3341007-B1 | MALT1 INHIBITORS AND USES THEREOF | UNIV CORNELL (US) | 2020-12-23 | — | — | EP | disclosed |
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | Cornell University Cornell Center for Technology Enterprise & Commercialization (CCTEC) (US) | 2018-09-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180251489-A1 | MALT1 INHIBITORS AND USES THEREOF | MALT1, BCL3, BCL6 | ELANE 2960/4885CCR1 1763/4885KMT2A 2424/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.