Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 1/20 | 0.41 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.41 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.41 |
| ▸ | BCHE | P06276 | 3/20 | 0.38 |
| ▸ | TLR7 | Q9NYK1 | 3/20 | 0.38 |
| ▸ | PARP1 | P09874 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | CNR1 | P21554 | 1/20 | 0.34 |
| ▸ | CNR2 | P34972 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DHODH | Q02127 | 1/20 | 0.33 |
| ▸ | ELANE | P08246 | 1/20 | 0.33 |
| ▸ | MPO | P05164 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL11036638 | 0.99 | PDE4A (0.40) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11038010 | 0.97 | TLR7 (0.42) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11036499 | 0.96 | TLR7 (0.43) | PDE4APDE4BPDE4CPDE4DBCHE | |
| Hydrochloric Acid SCHEMBL11036610 | 0.96 | TLR7 (0.41) | PDE4APDE4BPDE4CPDE4DBCHE | |
| Hydrochloric Acid SCHEMBL11037809 | 0.95 | TLR7 (0.43) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11265471 | 0.87 | TLR7 (0.41) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11254174 | 0.87 | TLR7 (0.41) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11251660 | 0.87 | BCHE (0.38) | BCHE | |
| Hydrochloric Acid SCHEMBL11266120 | 0.86 | TLR7 (0.40) | PDE4APDE4BPDE4CPDE4DBCHE | |
| SCHEMBL11258589 | 0.86 | TLR7 (0.40) | PDE4APDE4BPDE4CPDE4DBCHE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0038528-B1 | DIHYDRO-AS-TRIAZINO(5,6-C)QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1984-08-08 | — | — | EP | claimed |
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | claimed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | claimed |
| EP-0038528-B1 | DIHYDRO-AS-TRIAZINO(5,6-C)QUINOLINE DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1984-08-08 | — | — | EP | disclosed |
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |