Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 4/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.39 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.39 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.39 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 2/20 | 0.38 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | OXER1 | Q8TDS5 | 1/20 | 0.35 |
| ▸ | ELANE | P08246 | 2/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.33 |
| ▸ | TRPV1 | Q8NER1 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11254174 | 0.97 | TLR7 (0.41) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11265471 | 0.93 | TLR7 (0.41) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11266120 | 0.92 | TLR7 (0.40) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11038010 | 0.89 | TLR7 (0.42) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11036499 | 0.88 | TLR7 (0.43) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11036610 | 0.88 | TLR7 (0.41) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11037809 | 0.88 | TLR7 (0.43) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11038211 | 0.86 | PDE4A (0.41) | TLR7PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL11258031 | 0.86 | TLR7 (0.39) | TLR7PDE4APDE4BPDE4CPDE4D | |
| Hydrochloric Acid SCHEMBL11036638 | 0.85 | PDE4A (0.40) | TLR7PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4342766-A | SAID COMPOUNDS POSSESS ANTIPHLOGISTIC, ANALGESIC, ANTICONVULSIVE AND TRANQUILIZING PROPERTIES | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1982-08-03 | — | — | US | disclosed |
| EP-0038528-A1 | Dihydro-as-triazino(5,6-c)quinoline derivatives, process for their preparation and pharmaceutical compositions containing these compounds | EGYT GYOGYSZERVEGYESZETI GYAR (HU) | 1981-10-28 | — | — | EP | disclosed |
| US-4296256-A | 2-Decarboxy-2-hydroxymethyl-19-keto-PG compounds | THE UPJOHN COMPANY (US) | 1981-10-20 | — | — | US | disclosed |