SCHEMBL11038752

SCHEMBL11038752

Cc1c(C)c(C)c2ccccc2c1C.N=C=O.N=C=O

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP1A2 P05177 5/20 0.39
CYP3A4 P08684 4/20 0.37
TSHR P16473 4/20 0.37
HPGD P15428 3/20 0.37
HSD17B10 Q99714 3/20 0.37
L3MBTL1 Q9Y468 2/20 0.37
HIF1A Q16665 2/20 0.37
MAPK1 P28482 1/20 0.37
CASP1 P29466 1/20 0.37
RAB9A P51151 1/20 0.37
CASP7 P55210 1/20 0.37
ATM Q13315 1/20 0.37
CYP2A6 P11509 3/20 0.36
NPC1 O15118 1/20 0.36
HSP90AA1 P07900 1/20 0.36
GPR3 P46089 1/20 0.35
AHR P35869 1/20 0.34
TP53 P04637 2/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
CYP2D6 P10635 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL357443 0.83 CYP1A2 (0.53) CYP1A2CYP3A4TSHRHPGDHSD17B10
SCHEMBL29660297 0.83 CYP1A2 (0.53) CYP1A2CYP3A4TSHRHPGDHSD17B10
Hexamethylbenzene SCHEMBL28405817 0.81 TSHR (0.56) CYP1A2CYP3A4TSHRHPGDHSD17B10
Ammonia Solution, Strong SCHEMBL2263911 0.80 CYP1A2 (0.50) CYP1A2CYP3A4TSHRHPGDHSD17B10
Triphenylene SCHEMBL26965843 0.80 HPRT1 (0.40) CYP1A2CYP3A4TSHRHPGDHSD17B10
Triphenylene SCHEMBL9251630 0.80 HPRT1 (0.40) CYP1A2CYP3A4TSHRHPGDHSD17B10
SCHEMBL28539881 0.80 CYP1A2 (0.50) CYP1A2CYP3A4TSHRHPGDHSD17B10
Triphenylene SCHEMBL6233334 0.80 HPRT1 (0.40) CYP1A2CYP3A4TSHRHPGDHSD17B10
SCHEMBL9824756 0.79 CYP1A2 (0.68) CYP1A2CYP3A4TSHRHPGDHSD17B10
SCHEMBL29712920 0.79 CYP1A2 (0.68) CYP1A2CYP3A4TSHRHPGDHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-112143354-A Low-VOC (volatile organic compound) water-based coating composition with improved application performance 艾仕得涂料系统知识产权有限责任公司 2020-12-29 CN disclosed
EP-0149765-A2 Coating compositions containing a ketimine AMERICAN CYANAMID COMPANY (US) 1985-07-31 EP disclosed